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One major source of confusion comes from regulatory variations, where hydroquinone banned headlines often refer to restrictions in countries like EU member states, South Africa, and Australia
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These drugs include ondansetron (small benefit in a small randomized trial), S-adenosyl-methionine (SAMe, small benefit in uncontrolled studies), pentoxifylline (no benefit), modafinil (no benefit), hydroxyzine, zolpidem, trazodone, and melatonin (no benefit for sleep quality and insomnia) (8, 9)